【文献解读】血液灌流急救流程再造对急性中毒患者电解质紊乱、肝功能及预后的影响.docx

【文献解读】血液灌流急救流程再造对急性中毒患者电解质紊乱、肝功能及预后的影响武汉第三医院急诊科对2019年8月至2021年7月期间，137例参与急性中毒血液灌流急救流程再造的患者和151例进行常规急救的患者救治疗效进行对比，观察两组中毒救治的成功率、电解质、肝功能、预后和生存率。急救流程再造基于急诊血液净化临床应用专家共识和急诊基本情况，可归纳为四个方面：预审分诊、急诊对症治疗、快速转运、血液灌注。研究结果(Effectsofhemoperfusionfirstaidprocessreengineeringonelectrolytedisturbance,liverfunctionandprognosisinpatientswithacutepoisoning>(血液灌流急救流程改造对急性中毒患者电解质紊乱、肝功能及预后的影响)近期发表于BiotechnologyandGeneticEngineeringReviews期刊(IF:3.2)oEffectsofhemoperfusionfirstaidprocessreengineeringonelectrolytedisturbance,IiverfunctionandprognosisinpatientswithacutepoisoningShoupeng1.iaandYonghui1.iangbDepartmentofEmergencyMedicine,WuhanThirdHospital,TongrenHospitalAffiliatedtoWuhanUniversity,Wuhan,Hubei,China;bDepartmentofEmergencyandCriticalCareMedicine,TianyouHospitalAffiliatedtoWuhanUniversityofScienceandTechnology,Wuhan,Hubei,China结果显示急性中毒患者血液灌流急救流程再造后，提高急救成功率，缩短急救时间，改善患者电解质紊乱、治疗效果、肝功能和血常规。具体数据如下ClassifkatiObservationgroup(n=137)Controlgroup(n=151)/fPGender0.5670.451Male9295Female4556AgeAPACHEII11.16±2,O31152±2.151.4570.146Waysofpoisoning0.580.748Fd7587Respiratoryaspiration5256Skinexposure108Typesofpoisoning3.6490.161Pesticidepoisoning5949Drugpoisoning6385Others1517CombinedunderlyingdiseasesHypertension12150.1170.733Hyperlipidemia10171325025Diabetes13110.4570.499Coronaryheartdisease760.2150.643两组患者间的临床资料差异无统计学意义。Figure1.Comparisonofemergency-relatedindicators.(P<0.05vs.theobservationgroup).观察组诱导呕吐、中毒评估、静脉输血、意识恢复、血液净化回路打开、开始血液灌流的时间均短于对照组(P<0.05)oobservationgroupsajcontrolgroup0治疗前，两组A1.T、TBI1.SCr.BUN水平无差异(P>0.05)；治疗后，观察组的水平下降更为明显(P<0.05)Oobservationgroup-ucontrolgroup茨)9巴m2Jns观察组和对照组的死亡率分别为6.57%(9/137)和26.28%(41/151),差异有统计学意义(P<0.05)o扫码下载原文